When you walk out onto the bridge, 2 giant mutants come charging out of the building ahead. Run out onto the bridge and move onto the sloping edge on either side.
As soon as Lara targets one of the mutants, fire a rocket.
Then immediately flip to the other side of the bridge to avoid their blue energy bolts.
When Lara lands on her feet, quickly fire another rocket.
Then flip back to the other side. Repeat this twice more and you're done, since it only takes 2 rockets to kill each of the mutants. Just be sure to release the Action button as you jump so Lara doesn't waste rockets and take care not to fall off the bridge as you fight.
If you're out of rockets, my second-choice weapon would be the MP5. It can target the mutants at a fairly long distance.
So you can use the same basic strategy of flipping from side to side while shooting. You should be able to take out one of them that way.
If the second mutant rushes you, you may want to switch to the Uzis for close combat. If the mutant backs Lara into a corner, either roll to get on the other side of it or use a health pack and just keep firing until it falls.
If you fall off the bridge and survive, it's possible to climb back up on the right side when facing the end of the bridge where you entered this area, but it's probably just easier to reload and try again.
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